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M9630125.TXT
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1996-02-27
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Document 0125
DOCN M9630125
TI [Two cases of sensory neural hearing loss as a manifestation of HIV
infection]
DT 9603
AU Ohashi S; Hiraide F; Funasaka S; Fujita H; Yoshiura K; Hagiwara A; Fukue
H; Fukutake K; Department of Otorhinolaryngology, Tokyo Medical College.
SO Nippon Jibiinkoka Gakkai Kaiho. 1995 Sep;98(9):1399-406. Unique
Identifier : AIDSLINE MED/96021717
AB In patients with HIV infection, oral and pharyngeal pathology frequently
occurs, but there have been no reports on cases of deafness in Japan.
Herein, the authors report two cases of sensory neural hearing loss in
hemophilia A patients infected with HIV through factor VIII
concentrates. Case 1 was a 16-year-old male with hemophilia A. He had
been administered factor VIII concentrates starting at 6 months after
birth. At 8 years of age, HIV antibodies were positive. He was diagnosed
as having AIDS after suffering from pneumocystis carinii. He complained
of right otalgia and slight vertigo during treatment for a relapse of
the pneumocystis carinii. He underwent otological examinations at our
department. The right tympanic membrane showed opacification and serous
otorrhea was noted. Acute otitis media was diagnosed and tympanotomy was
conducted. Afterwards, the right tympanic membrane developed a large
perforation and sensory neural hearing loss occurred. Case 2 was a
49-year-old male with hemophilia A. He had been administered factor VIII
concentrates from the age of 23 years. At 48 years of age, HIV
antibodies were positive. The patient complained of sudden deafness in
the right ear and slight vertigo. He underwent otological examinations
at our department. The tympanic membrane was normal bilaterally, but
sensory neural hearing loss was found in the right ear. It was presumed
that acute otitis media directly involving the inner ear had caused a
perceptive disorder in case 1 while a pattern of sudden onset of
deafness was apparent in case 2.
DE Acquired Immunodeficiency Syndrome/*COMPLICATIONS/TRANSMISSION
Adolescence Case Report English Abstract Factor VIII/ADVERSE EFFECTS
Hearing Loss, Sensorineural/*ETIOLOGY Hemophilia/COMPLICATIONS Human
Male Middle Age JOURNAL ARTICLE REVIEW REVIEW OF REPORTED CASES
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).